iPTMnet Report for Q15223 (NECTIN1)
Protein Information
UniProt AC / UniProt ID | Q15223 / NECT1_HUMAN |
Protein Name | Nectin-1 precursor |
Gene Name | Name: NECTIN1 Synonyms:HVEC,PRR1,PVRL1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15223 |
PRO Name | nectin-1 (human) |
Definition | A nectin-1 that is encoded in the genome of human. |
Short Label | hNECTIN1 |
Category | organism-gene |
Q15223 (NECTIN1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
S59 | Phosphorylation | score1 | PhosphoSitePlus | |||
N72 | N-Glycosylation | score3 | GlyGen UniProt | 21980294 | ||
N139 | N-Glycosylation | score4 | GlyGen UniProt | 23090970, 29741879, 21980294, ... | ||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
N200 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N202 | N-Glycosylation | score4 | GlyGen UniProt | 16335952, 24190977, 23090970, ... | ||
Y211 | Phosphorylation | score1 | PhosphoSitePlus | |||
N286 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N297 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
N307 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N332 | N-Glycosylation | score2 | GlyGen UniProt | 19349973 | ||
T339 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y389 | Phosphorylation | score1 | PhosphoSitePlus | |||
S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
T391 | Phosphorylation | score1 | PhosphoSitePlus | |||
K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y396 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y400 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y418 | Phosphorylation | score1 | PhosphoSitePlus | |||
S422 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
K427 | Ubiquitination | score1 | PhosphoSitePlus | |||
S434 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y436 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y460 | Phosphorylation | score1 | PhosphoSitePlus | |||
K465 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y468 | Phosphorylation | score1 | PhosphoSitePlus | |||
T470 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y481 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y488 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y490 | Phosphorylation | score1 | PhosphoSitePlus | |||
S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
S511 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S59 | N59 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
N202 | S202 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
N307 | D307 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K427 | M427 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S435 | T435 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y468 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] |