iPTMnet Report Q15173 PPP2R5B

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q15173 / 2A5B_HUMAN
Protein Name	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Gene Name	Name: PPP2R5B
Organism	Homo sapiens (Human)

PRO ID	PR:Q15173 DAG View
PRO Name	serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (human)
Definition	A serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform that is encoded in the genome of human.
Short Label	hPPP2R5B
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q15173 (PPP2R5B) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S16	Phosphorylation		score1	PhosphoSitePlus
	S20	Phosphorylation		score1	PhosphoSitePlus
	S32	Phosphorylation		score2	UniProt	21329884
	S35	Phosphorylation		score3	PhosphoSitePlus UniProt	21329884
	S44	Phosphorylation		score3	PhosphoSitePlus UniProt	21329884
	S46	Phosphorylation		score3	PhosphoSitePlus UniProt	21329884
	S47	Phosphorylation		score3	PhosphoSitePlus UniProt	21329884
	S48	Phosphorylation		score3	PhosphoSitePlus UniProt	21329884
	Y52	Phosphorylation		score1	PhosphoSitePlus
	Y126	Phosphorylation		score1	PhosphoSitePlus
	S368	Phosphorylation		score2	PRO PhosphoSitePlus
	K479	Ubiquitination		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S20	Phosphorylation		score0	HPRD	17322306

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000048888 (hPPP2R5B/Phos:1)	pS368		PRO

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S16	F16	Biomuta		[ cosmic ]
S20	W20	Biomuta		DOID:4362 / cervical cancer [ cosmic, icgc ]
S32	F32	Biomuta		DOID:3571 / liver cancer [ cosmic, icgc ]