Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15049 / MLC1_HUMAN
Protein Name Membrane protein MLC1
Gene Name Name: MLC1
Synonyms:KIAA0027,WKL1;
Organism Homo sapiens (Human)

PRO ID PR:Q15049
DAG View
PRO Name membrane protein MLC1 (human)
Definition A membrane protein MLC1 that is encoded in the genome of human.
Short Label hMLC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15049 (MLC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T17 Phosphorylation PhosphoSitePlus
Y28 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T17 M17 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K175 E175 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K175 T175 Biomuta DOID:1324 / lung cancer [ cosmic ]