iPTMnet Report for Q15032 (R3HDM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15032 / R3HD1_HUMAN
Protein Name R3H domain-containing protein 1
Gene Name Name: R3HDM1
Synonyms:KIAA0029,R3HDM;
Organism Homo sapiens (Human)

PRO ID PR:Q15032
DAG View
PRO Name R3H domain-containing protein 1 (human)
Definition An R3H domain-containing protein 1 that is encoded in the genome of human.
Short Label hR3HDM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15032 (R3HDM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
T13 Phosphorylation PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
K131 Acetylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S197 O-Glycosylation GlyGen 23301498, 29351928, 35138101, ...30379171, 32574038, 30059200, 35254053, 30620550
Y198 Phosphorylation PhosphoSitePlus
S229 O-Glycosylation GlyGen 23301498, 29351928, 35138101, ...30379171, 32574038, 30059200, 35254053, 30620550
Y254 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus   UniProt 23186163
S280 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus   UniProt 23186163
S305 Phosphorylation PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
S337 Phosphorylation phospho.ELM 15144186
S347 Phosphorylation PhosphoSitePlus
Y354 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
T377 O-Glycosylation GlyGen 23301498, 29351928, 35138101, ...30379171, 32574038, 30059200, 35254053, 30620550
S380 Phosphorylation PhosphoSitePlus   UniProt 21406692
S381 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S383 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus   UniProt 23186163
S399 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
S484 Phosphorylation IEDB 32387766
S501 Phosphorylation PhosphoSitePlus
Y646 Phosphorylation PhosphoSitePlus
S806 Phosphorylation PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
Y857 Phosphorylation PhosphoSitePlus
S888 Phosphorylation PhosphoSitePlus
S892 Phosphorylation PhosphoSitePlus
R929 Methylation PhosphoSitePlus   UniProt 24129315
S973 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17287340, 19690332
T974 Phosphorylation PhosphoSitePlus
K985 Ubiquitination PhosphoSitePlus
K1003 Ubiquitination PhosphoSitePlus
S1034 Phosphorylation PhosphoSitePlus
S1075 Phosphorylation PhosphoSitePlus
K1078 Ubiquitination PhosphoSitePlus
Y1088 Phosphorylation PhosphoSitePlus
S1097 Phosphorylation PhosphoSitePlus
S1098 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S142 Phosphorylation HPRD 18669648
Y145 Phosphorylation HPRD 18452278
S187 Phosphorylation HPRD 19651622, 18669648, 20068231
S262 Phosphorylation HPRD 17081983
S280 Phosphorylation HPRD 18452278
S282 Phosphorylation HPRD 18452278
S347 Phosphorylation HPRD 19651622
S381 Phosphorylation HPRD 15144186, 18767875, 18669648, ...18212344, 20068231
S383 Phosphorylation HPRD 15570572
S399 Phosphorylation HPRD 20068231
S973 Phosphorylation HPRD 17287340
Site PTM Type PTM Enzyme Score Source PMID
S67 Phosphorylation PhosphoSitePlus
S293 Phosphorylation phospho.ELM 18669648
S372 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 F4 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T13 S13 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K24 E24 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K24 T24 Biomuta DOID:263 / kidney cancer [ cosmic ]
K40 N40 Biomuta DOID:1324 / lung cancer [ cosmic ]
S141 F141 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y145 C145 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S187 Y187 Biomuta DOID:363 / uterine cancer [ icgc ]
S262 I262 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
R286 I286 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S305 F305 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S355 L355 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S380 G380 Biomuta DOID:1612 / breast cancer [ cosmic ]
S393 N393 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S393 I393 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y646 C646 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y857 D857 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S888 L888 Biomuta [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S1098 Y1098 Biomuta DOID:9256 / colorectal cancer [ icgc ]