iPTMnet Report for Q15027 (ACAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15027 / ACAP1_HUMAN
Protein Name Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Gene Name Name: ACAP1
Synonyms:CENTB1,KIAA0050;
Organism Homo sapiens (Human)

PRO ID PR:Q15027
DAG View
PRO Name Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (human)
Definition An Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 that is encoded in the genome of human.
Short Label hACAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15027 (ACAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Acetylation PhosphoSitePlus
K4 Ubiquitination PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
C79 Methylation IEDB 31844290
K82 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
S258 O-Glycosylation GlyGen 33214551, 29351928
K274 Acetylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
Y297 Phosphorylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
T306 O-Glycosylation GlyGen 33214551, 29351928
T306 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
S554 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 16256741
S554 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus   Signor 16256741
K558 Ubiquitination PhosphoSitePlus
T711 Phosphorylation PhosphoSitePlus
Y712 Phosphorylation HPRD   PhosphoSitePlus 15592455
S720 Phosphorylation PhosphoSitePlus
K729 Ubiquitination PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
T739 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C79 Y79 Biomuta DOID:1319 / brain cancer [ icgc ]
C79 F79 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K114 R114 Biomuta DOID:1612 / breast cancer [ cosmic ]
K185 T185 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S277 N277 Biomuta DOID:4159 / skin cancer [ cosmic ]
S392 P392 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K506 E506 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K522 R522 Biomuta DOID:4159 / skin cancer [ cosmic ]