iPTMnet Report for Q15018 (ABRAXAS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15018 / ABRX2_HUMAN
Protein Name BRISC complex subunit Abraxas 2
Gene Name Name: ABRAXAS2
Synonyms:ABRO1;
Organism Homo sapiens (Human)

PRO ID PR:Q15018
DAG View
PRO Name BRISC complex subunit Abraxas 2 (human)
Definition A BRISC complex subunit Abraxas 2 that is encoded in the genome of human.
Short Label hABRAXAS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15018 (ABRAXAS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K74 Ubiquitination PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
T168 Phosphorylation HPRD 20068231
S169 Phosphorylation HPRD 20068231
Y173 Phosphorylation HPRD 20068231
K174 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
C224 Methylation IEDB 31844290
K229 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
K255 Acetylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus   UniProt 23186163
S280 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S302 Phosphorylation PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
Y342 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15144186
S344 Phosphorylation PhosphoSitePlus
T345 O-Glycosylation GlyGen 34725712, 31373491, 28510447
T345 Phosphorylation PhosphoSitePlus
S346 O-Glycosylation GlyGen 31373491
S346 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
S368 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 19415658, ...19651622, 18669648, 18452278, 19690332
S372 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18452278, 19651622, ...18669648, 19415658, 19690332
S375 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18452278, 19651622, ...18669648, 19415658, 19690332
Y377 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18452278
S394 Phosphorylation PhosphoSitePlus
T410 Phosphorylation PhosphoSitePlus
S413 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T101 M101 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
Y173 N173 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K199 N199 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C224 Y224 Biomuta DOID:1324 / lung cancer [ cosmic ]
S309 F309 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S339 Y339 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S344 Y344 Biomuta DOID:1612 / breast cancer [ cosmic ]
S346 N346 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S394 L394 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]