iPTMnet Report for Q14781 (CBX2)
Protein Information
UniProt AC / UniProt ID | Q14781 / CBX2_HUMAN |
Protein Name | Chromobox protein homolog 2 |
Gene Name | Name: CBX2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q14781 |
PRO Name | chromobox protein homolog 2 (human) |
Definition | A chromobox protein homolog 2 that is encoded in the genome of human. |
Short Label | hCBX2 |
Category | organism-gene |
Q14781 (CBX2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C16 | Methylation | score1 | IEDB | 31844290 | ||
K60 | Sumoylation | score1 | PhosphoSitePlus | |||
T84 | Phosphorylation | score1 | PhosphoSitePlus | |||
S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
S104 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
S120 | Phosphorylation | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
K146 | Sumoylation | score1 | PhosphoSitePlus | |||
K153 | Sumoylation | score1 | PhosphoSitePlus | |||
S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
K199 | Acetylation | score1 | PhosphoSitePlus | |||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
T230 | Phosphorylation | score1 | PhosphoSitePlus | |||
R247 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
Y259 | Phosphorylation | score1 | PhosphoSitePlus | |||
K277 | Methylation | score1 | PhosphoSitePlus | |||
K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
T281 | Phosphorylation | score1 | PhosphoSitePlus | |||
K283 | Methylation | score1 | PhosphoSitePlus | |||
K283 | Ubiquitination | score1 | PhosphoSitePlus | |||
K291 | Ubiquitination | score1 | PhosphoSitePlus | |||
T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
S302 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
K320 | Sumoylation | score1 | PhosphoSitePlus | |||
K320 | Ubiquitination | score1 | PhosphoSitePlus | |||
K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
K390 | Ubiquitination | score1 | PhosphoSitePlus | |||
K410 | Sumoylation | score1 | PhosphoSitePlus | |||
T423 | Phosphorylation | score1 | PhosphoSitePlus | |||
K427 | Ubiquitination | score1 | PhosphoSitePlus | |||
K432 | Ubiquitination | score1 | PhosphoSitePlus | |||
S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
T436 | Phosphorylation | score1 | PhosphoSitePlus | |||
S438 | Phosphorylation | score1 | PhosphoSitePlus | |||
S520 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C16 | F16 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K96 | N96 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S104 | F104 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S120 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
K184 | N184 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K191 | E191 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
R247 | W247 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
R247 | L247 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K277 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
T281 | A281 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T294 | M294 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
K379 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K379 | N379 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K427 | M427 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |