iPTMnet Report for Q14765 (STAT4)
Protein Information
| UniProt AC / UniProt ID | Q14765 / STAT4_HUMAN |
| Protein Name | Signal transducer and activator of transcription 4 |
| Gene Name | Name: STAT4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14765 |
| PRO Name | signal transducer and activator of transcription 4 (human) |
| Definition | A signal transducer and activator of transcription 4 that is encoded in the genome of human. |
| Short Label | hSTAT4 |
| Category | organism-gene |
DAG ViewQ14765 (STAT4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K151 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T287 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T298 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S362 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T369 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S371 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S386 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S394 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S396 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K562 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y645 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K667 | Acetylation | score3 | PhosphoSitePlus UniProt | 35614130 | ||
| K691 | Acetylation | score1 | PhosphoSitePlus | |||
| Y693 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 28877912, 24842371, 32213463, ... | ||
| Y693 | Phosphorylation | O60674 (JAK2) | score1 | Signor | 16324152 | |
| S713 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S721 | Phosphorylation | score4 | HPRD neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 10961885, 16324152, 17502367 | ||
| S721 | Phosphorylation | P52564 (MAP2K6) | score1 | HPRD | 10961885 | |
| S721 | Phosphorylation | Q16539 (MAPK14) | score4 | HPRD neXtProt Signor | 10961885, 17502367 | |
| S733 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T735 | O-Glycosylation | score1 | GlyGen | 30379171, 29351928 | ||
| T736 | O-Glycosylation | score1 | GlyGen | 30379171, 29351928 | ||
| T739 | O-Glycosylation | score1 | GlyGen | 30379171, 29351928 | ||
| S743 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y745 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S746 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S130 | F130 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K151 | R151 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T287 | A287 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y288 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S362 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
| T369 | A369 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S371 | I371 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S386 | Y386 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| S386 | F386 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S396 | * | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
| S721 | Y721 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| S743 | Y743 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
