iPTMnet Report for Q14697 (GANAB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14697 / GANAB_HUMAN
Protein Name Neutral alpha-glucosidase AB precursor
Gene Name Name: GANAB
Synonyms:G2AN,KIAA0088;
Organism Homo sapiens (Human)

PRO ID PR:Q14697
DAG View
PRO Name neutral alpha-glucosidase AB (human)
Definition A neutral alpha-glucosidase AB that is encoded in the genome of human.
Short Label hGANAB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14697 (GANAB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S36 Phosphorylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
C47 Methylation IEDB 31844290
C47 S-Nitrosylation dbSNO 2212679, 22126794
K48 Acetylation PhosphoSitePlus
K48 Methylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus   UniProt 23186163
S58 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
N97 N-Glycosylation GlyGen   UniProt 3881423
T141 Phosphorylation PhosphoSitePlus
R164 Methylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
R182 Methylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
R206 Methylation PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
Y396 Phosphorylation PhosphoSitePlus
K436 Acetylation PhosphoSitePlus
T451 O-Glycosylation GlyGen 35008409, 33214551, 30397120, ...34725712, 26853435, 34019948, 35083852, 32870666, 32119511, 28510447, 33465208
K462 Acetylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K472 Sumoylation PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
R484 Methylation PhosphoSitePlus
Y489 Phosphorylation PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
Y563 Phosphorylation PhosphoSitePlus
Y578 Phosphorylation PhosphoSitePlus
R590 Methylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
R698 Methylation PhosphoSitePlus
R720 Methylation PhosphoSitePlus
T790 Phosphorylation PhosphoSitePlus
Y792 Phosphorylation PhosphoSitePlus
T796 Phosphorylation PhosphoSitePlus
T808 Phosphorylation PhosphoSitePlus
S820 Phosphorylation PhosphoSitePlus
R863 Methylation PhosphoSitePlus
S866 Phosphorylation PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
K899 Ubiquitination PhosphoSitePlus
K908 Ubiquitination PhosphoSitePlus
K930 Ubiquitination PhosphoSitePlus
S937 Phosphorylation PhosphoSitePlus
R944 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T204 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K204 Ubiquitination PhosphoSitePlus
T226 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N97 D97 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R164 Q164 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S190 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R206 S206 Biomuta DOID:1324 / lung cancer [ cosmic ]
K217 R217 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K231 R231 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K231 E231 Biomuta DOID:1324 / lung cancer [ cosmic ]
K237 N237 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S345 F345 Biomuta DOID:4159 / skin cancer [ cosmic ]
K472 T472 Biomuta DOID:4159 / skin cancer [ cosmic ]
R484 W484 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R484 Q484 Biomuta DOID:363 / uterine cancer [ icgc ]
R590 H590 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S608 F608 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S608 C608 Biomuta DOID:1324 / lung cancer [ cosmic ]
R698 Q698 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R720 L720 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T790 P790 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S820 L820 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R863 H863 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S866 L866 Biomuta DOID:4362 / cervical cancer [ icgc ]
S937 Y937 Biomuta DOID:1324 / lung cancer [ cosmic ]