iPTMnet Report for Q14696 (MESD)
Protein Information
UniProt AC / UniProt ID | Q14696 / MESD_HUMAN |
Protein Name | LRP chaperone MESD precursor |
Gene Name | Name: MESD Synonyms:KIAA0081,MESDC2,MESDM;ORFNames:UNQ1911/PRO4369; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q14696 |
PRO Name | LRP chaperone MESD (human) |
Definition | A mesoderm development candidate 2 that is encoded in the genome of human. |
Short Label | hMESD |
Category | organism-gene |
Q14696 (MESD) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C32 | Methylation | score1 | IEDB | 31844290 | ||
Y58 | Phosphorylation | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
S88 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
S88 | Phosphorylation | score1 | PhosphoSitePlus | |||
K95 | Methylation | score1 | PhosphoSitePlus | |||
T113 | Phosphorylation | score1 | PhosphoSitePlus | |||
S121 | Phosphorylation | score1 | PhosphoSitePlus | |||
S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
T125 | Phosphorylation | score1 | PhosphoSitePlus | |||
R179 | Methylation | score1 | PhosphoSitePlus | |||
K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
K211 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K95 | M95 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K95 | T95 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T125 | A125 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |