iPTMnet Report for Q14679 (TTLL4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14679 / TTLL4_HUMAN
Protein Name Tubulin monoglutamylase TTLL4
Gene Name Name: TTLL4
Synonyms:KIAA0173;
Organism Homo sapiens (Human)

PRO ID PR:Q14679
DAG View
PRO Name tubulin monoglutamylase TTLL4 (human)
Definition A tubulin monoglutamylase TTLL4 that is encoded in the genome of human.
Short Label hTTLL4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14679 (TTLL4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y9 Phosphorylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S152 O-Glycosylation GlyGen 35254053
S156 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
K646 Acetylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus   UniProt 19690332
S696 Phosphorylation PhosphoSitePlus
Y768 Phosphorylation PhosphoSitePlus
Y770 Phosphorylation PhosphoSitePlus
Y774 Phosphorylation PhosphoSitePlus
C829 Methylation IEDB 31844290
K833 Ubiquitination PhosphoSitePlus
K856 Ubiquitination PhosphoSitePlus
T864 Phosphorylation PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
Y871 Phosphorylation PhosphoSitePlus
S912 Phosphorylation PhosphoSitePlus
K981 Ubiquitination PhosphoSitePlus
K1062 Ubiquitination PhosphoSitePlus
K1108 Ubiquitination PhosphoSitePlus
K1136 Ubiquitination PhosphoSitePlus
K1137 Ubiquitination PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus
K1160 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y9 C9 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K58 T58 Biomuta DOID:3571 / liver cancer [ cosmic ]
S144 N144 Biomuta [ cosmic ]
S156 T156 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T412 I412 Biomuta DOID:363 / uterine cancer [ icgc ]
S867 L867 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y871 C871 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1143 F1143 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1143 Y1143 Biomuta DOID:363 / uterine cancer [ icgc ]