iPTMnet Report for Q14558 (PRPSAP1)
Protein Information
| UniProt AC / UniProt ID | Q14558 / KPRA_HUMAN |
| Protein Name | Phosphoribosyl pyrophosphate synthase-associated protein 1 |
| Gene Name | Name: PRPSAP1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14558 |
| PRO Name | phosphoribosyl pyrophosphate synthase-associated protein 1 (human) |
| Definition | A phosphoribosyl pyrophosphate synthase-associated protein 1 that is encoded in the genome of human. |
| Short Label | hPRPSAP1 |
| Category | organism-gene |
Q14558 (PRPSAP1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 19413330 | ||
| K24 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y168 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S177 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S186 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S215 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569 | ||
| K238 | Acetylation | score1 | PhosphoSitePlus | |||
| K238 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y281 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K317 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T234 | M234 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T234 | K234 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
DAG View