iPTMnet Report for Q14353 (GAMT)
Protein Information
| UniProt AC / UniProt ID | Q14353 / GAMT_HUMAN |
| Protein Name | Guanidinoacetate N-methyltransferase |
| Gene Name | Name: GAMT |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q14353 |
| PRO Name | guanidinoacetate N-methyltransferase (human) |
| Definition | A guanidinoacetate N-methyltransferase that is encoded in the genome of human. |
| Short Label | hGAMT |
| Category | organism-gene |
DAG ViewQ14353 (GAMT) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 22223895 | ||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K60 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y223 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K235 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K109 | N109 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y223 | C223 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
