iPTMnet Report for Q14320 (FAM50A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14320 / FA50A_HUMAN
Protein Name Protein FAM50A
Gene Name Name: FAM50A
Synonyms:DXS9928E,HXC26,XAP5;
Organism Homo sapiens (Human)

PRO ID PR:Q14320
DAG View
PRO Name protein FAM50A (human)
Definition A protein FAM50A that is encoded in the genome of human.
Short Label hFAM50A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14320 (FAM50A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
Y4 Phosphorylation PhosphoSitePlus
K5 Methylation PhosphoSitePlus
K5 Sumoylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
R13 Methylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K48 Acetylation PhosphoSitePlus
K48 Sumoylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
Y53 Phosphorylation PhosphoSitePlus
S62 Phosphorylation HPRD 20068231
S63 Phosphorylation HPRD 20068231
T64 Phosphorylation HPRD 20068231
K74 Ubiquitination PhosphoSitePlus
K76 Sumoylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K91 Acetylation PhosphoSitePlus
S94 Phosphorylation HPRD   PhosphoSitePlus 20068231
K95 Methylation PhosphoSitePlus
K100 Sumoylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
R170 Methylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K195 Acetylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K236 Methylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
R242 Methylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K275 Sumoylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K305 Sumoylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
R309 Methylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K42 N42 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S50 F50 Biomuta [ cosmic ]
S63 G63 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T64 I64 Biomuta [ cosmic ]
T64 N64 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S118 Y118 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T123 A123 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T123 I123 Biomuta DOID:4159 / skin cancer [ cosmic ]
R170 Q170 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K195 N195 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R242 S242 Biomuta DOID:1319 / brain cancer [ cosmic ]
S276 T276 Biomuta DOID:1324 / lung cancer [ cosmic ]
K305 N305 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K305 M305 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K305 T305 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K331 N331 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]