iPTMnet Report for Q14209 (E2F2)
Protein Information
UniProt AC / UniProt ID | Q14209 / E2F2_HUMAN |
Protein Name | Transcription factor E2F2 |
Gene Name | Name: E2F2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q14209 |
PRO Name | transcription factor E2F2 (human) |
Definition | A transcription factor E2F2 that is encoded in the genome of human. |
Short Label | hE2F2 |
Category | organism-gene |
Q14209 (E2F2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T15 | Phosphorylation | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
T104 | Phosphorylation | score1 | PhosphoSitePlus | |||
S117 | Phosphorylation | score1 | PhosphoSitePlus | |||
K119 | Acetylation | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
T120 | Phosphorylation | score1 | PhosphoSitePlus | |||
K122 | Acetylation | score1 | PhosphoSitePlus | |||
S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
K127 | Acetylation | score1 | PhosphoSitePlus | |||
Y130 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 | ||
S133 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 | ||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
K236 | Ubiquitination | score1 | PhosphoSitePlus | |||
K245 | Acetylation | score1 | PhosphoSitePlus | |||
K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
K270 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K119 | Acetylation | score2 | PRO | 10753885 | ||
K119 | Acetylation | PR:000027108 (h(CBP-p300)) | score2 | PRO | 10753885 | |
K122 | Acetylation | score2 | PRO | 10753885 | ||
K122 | Acetylation | PR:000027108 (h(CBP-p300)) | score2 | PRO | 10753885 | |
K127 | Acetylation | score2 | PRO | 10753885 | ||
K127 | Acetylation | PR:000027108 (h(CBP-p300)) | score2 | PRO | 10753885 |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000028774 (hE2F2/iso:1/Ac:1) | acK119,acK122,acK127 | PR:000027108 (h(CBP-p300)) | PRO | 10753885 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T120 | I120 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ] | |
K122 | N122 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K270 | E270 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |