iPTMnet Report for Q14186 (TFDP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14186 / TFDP1_HUMAN
Protein Name Transcription factor Dp-1
Gene Name Name: TFDP1
Synonyms:DP1;
Organism Homo sapiens (Human)

PRO ID PR:Q14186
DAG View
PRO Name transcription factor Dp-1 (human)
Definition A transcription factor Dp-1 that is encoded in the genome of human.
Short Label hTFDP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14186 (TFDP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Acetylation PhosphoSitePlus   UniProt 19608861
K3 Ubiquitination PhosphoSitePlus
S23 Phosphorylation O14757 (CHEK1) phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...21851590, 19690332, 20068231
K26 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K301 Acetylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
T388 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation HPRD 19413330, 17322306, 20058876, ...19664994, 19007248, 19664995, 19651622, 18669648, 18767875, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 N23 Biomuta DOID:4159 / skin cancer [ cosmic ]
S23 R23 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K126 E126 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S183 Y183 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S183 F183 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K190 R190 Biomuta DOID:3571 / liver cancer [ cosmic ]
K320 Q320 Biomuta DOID:9256 / colorectal cancer [ cosmic ]