iPTMnet Report for Q14159 (SPIDR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14159 / SPIDR_HUMAN
Protein Name DNA repair-scaffolding protein
Gene Name Name: SPIDR
Synonyms:KIAA0146;
Organism Homo sapiens (Human)

PRO ID PR:Q14159
DAG View
PRO Name DNA repair-scaffolding protein (human)
Definition A DNA repair-scaffolding protein that is encoded in the genome of human.
Short Label hSPIDR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14159 (SPIDR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation PhosphoSitePlus
K84 Sumoylation PhosphoSitePlus
T88 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
R259 Methylation PhosphoSitePlus
Y287 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus
T514 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus
T559 Phosphorylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
T582 Phosphorylation PhosphoSitePlus
T594 Phosphorylation PhosphoSitePlus
Y603 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
Y623 Phosphorylation PhosphoSitePlus
R646 Methylation PhosphoSitePlus
T693 Phosphorylation IEDB 32387766
C777 Methylation IEDB 31844290
S826 Phosphorylation PhosphoSitePlus
S857 Phosphorylation PhosphoSitePlus
K873 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S252 * Biomuta DOID:4159 / skin cancer [ cosmic ]
R259 I259 Biomuta DOID:2021 / placenta cancer [ cosmic ]
Y623 D623 Biomuta DOID:363 / uterine cancer [ icgc ]
S857 P857 Biomuta DOID:2531 / hematologic cancer [ cosmic ]