iPTMnet Report for Q13889 (GTF2H3)
Protein Information
UniProt AC / UniProt ID | Q13889 / TF2H3_HUMAN |
Protein Name | General transcription factor IIH subunit 3 |
Gene Name | Name: GTF2H3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13889 |
PRO Name | general transcription factor IIH subunit 3 (human) |
Definition | A general transcription factor IIH subunit 3 that is encoded in the genome of human. |
Short Label | hGTF2H3 |
Category | organism-gene |
Q13889 (GTF2H3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K125 | Sumoylation | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
C142 | Methylation | score1 | IEDB | 31844290 | ||
K152 | Ubiquitination | score1 | PhosphoSitePlus | |||
S239 | Phosphorylation | score1 | PhosphoSitePlus | |||
C268 | Methylation | score1 | IEDB | 31844290 | ||
K298 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K116 | N116 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K121 | N121 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
C268 | Y268 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |