iPTMnet Report for Q13751 (LAMB3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13751 / LAMB3_HUMAN
Protein Name Laminin subunit beta-3 precursor
Gene Name Name: LAMB3
Synonyms:LAMNB1;
Organism Homo sapiens (Human)

PRO ID PR:Q13751
DAG View
PRO Name laminin subunit beta-3 (human)
Definition A laminin subunit beta-3 that is encoded in the genome of human.
Short Label hLAMB3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13751 (LAMB3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
N220 N-Glycosylation GlyGen 23090970, 24190977
K414 Ubiquitination PhosphoSitePlus
N604 N-Glycosylation GlyGen 23090970, 24190977
T606 O-Glycosylation GlyGen 35289036, 21526146
K705 Sumoylation PhosphoSitePlus
K705 Ubiquitination PhosphoSitePlus
S712 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K766 Ubiquitination PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
N810 N-Glycosylation GlyGen 23090970, 24190977
T812 Phosphorylation PhosphoSitePlus
S816 Phosphorylation PhosphoSitePlus
K953 Ubiquitination PhosphoSitePlus
S971 Phosphorylation PhosphoSitePlus
K1027 Ubiquitination PhosphoSitePlus
K1034 Ubiquitination PhosphoSitePlus
K1084 Ubiquitination PhosphoSitePlus
K1089 Ubiquitination PhosphoSitePlus
K1109 Sumoylation PhosphoSitePlus
K1109 Ubiquitination PhosphoSitePlus
K1127 Methylation PhosphoSitePlus
K1152 Ubiquitination PhosphoSitePlus
T1170 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K188 N188 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
N220 D220 Biomuta DOID:4362 / cervical cancer [ cosmic ]
K414 T414 Biomuta DOID:1324 / lung cancer [ cosmic ]
T606 N606 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T606 I606 Biomuta DOID:1319 / brain cancer [ cosmic ]
S712 L712 Biomuta DOID:4159 / skin cancer [ cosmic ]
N810 S810 Biomuta DOID:3571 / liver cancer [ cosmic ]
S816 F816 Biomuta DOID:4159 / skin cancer [ cosmic ]
S971 N971 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1027 R1027 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1084 N1084 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K1127 R1127 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]