iPTMnet Report for Q13596 (SNX1)
Protein Information
UniProt AC / UniProt ID | Q13596 / SNX1_HUMAN |
Protein Name | Sorting nexin-1 |
Gene Name | Name: SNX1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13596 |
PRO Name | sorting nexin-1 (human) |
Definition | A sorting nexin-1 that is encoded in the genome of human. |
Short Label | hSNX1 |
Category | organism-gene |
Q13596 (SNX1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S25 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S32 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569 | ||
S39 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569 | ||
T41 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T48 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569 | ||
S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
S58 | Phosphorylation | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y131 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y162 | Phosphorylation | score1 | PhosphoSitePlus | |||
S172 | Phosphorylation | score1 | PhosphoSitePlus | |||
K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
S188 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 18669648, 24275569, ... | ||
Y194 | Phosphorylation | score1 | PhosphoSitePlus | |||
K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
K200 | Ubiquitination | score1 | PhosphoSitePlus | |||
S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
K237 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
R262 | Methylation | score1 | PhosphoSitePlus | |||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
T276 | Phosphorylation | score1 | PhosphoSitePlus | |||
T278 | Phosphorylation | score1 | PhosphoSitePlus | |||
S280 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
K297 | Ubiquitination | score1 | PhosphoSitePlus | |||
K325 | Ubiquitination | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
S368 | Phosphorylation | score1 | PhosphoSitePlus | |||
K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
K445 | Ubiquitination | score1 | PhosphoSitePlus | |||
K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
K490 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y502 | Phosphorylation | score1 | PhosphoSitePlus | |||
K519 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S25 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S32 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231, ... | ||
S39 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
T41 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 18452278 | ||
T48 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
S72 | Phosphorylation | score0 | HPRD | 19651622 | ||
S188 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S25 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S32 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231, ... | ||
S39 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
T41 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 18452278 | ||
T48 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
S72 | Phosphorylation | score0 | HPRD | 19651622 | ||
S123 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | P3 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T41 | A41 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S54 | N54 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
S64 | F64 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S123 | G123 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] | |
S188 | G188 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y194 | H194 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T276 | I276 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K286 | N286 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
K490 | N490 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |