iPTMnet Report for Q13503 (MED21)
Protein Information
UniProt AC / UniProt ID | Q13503 / MED21_HUMAN |
Protein Name | Mediator of RNA polymerase II transcription subunit 21 |
Gene Name | Name: MED21 Synonyms:SRB7,SURB7; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13503 |
PRO Name | mediator of RNA polymerase II transcription subunit 21 (human) |
Definition | A mediator of RNA polymerase II transcription subunit 21 that is encoded in the genome of human. |
Short Label | hMED21 |
Category | organism-gene |
Q13503 (MED21) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
S78 | Phosphorylation | score1 | IEDB | 32387766 | ||
Y91 | Phosphorylation | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
S144 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K67 | T67 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
Y91 | C91 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] |