iPTMnet Report for Q13332 (PTPRS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13332 / PTPRS_HUMAN
Protein Name Receptor-type tyrosine-protein phosphatase S precursor
Gene Name Name: PTPRS
Organism Homo sapiens (Human)

PRO ID PR:Q13332
DAG View
PRO Name receptor-type tyrosine-protein phosphatase S (human)
Definition A receptor-type tyrosine-protein phosphatase S that is encoded in the genome of human.
Short Label hPTPRS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13332 (PTPRS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y214 Phosphorylation PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
N263 N-Glycosylation GlyGen   UniProt 25385546
N308 N-Glycosylation GlyGen   UniProt 25385546
Y556 Phosphorylation PhosphoSitePlus
R610 Methylation PhosphoSitePlus
S708 Phosphorylation PhosphoSitePlus
N733 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 24190977, ...19159218, 19349973
T803 Phosphorylation PhosphoSitePlus
Y812 Phosphorylation PhosphoSitePlus
T813 Phosphorylation PhosphoSitePlus
T843 Phosphorylation PhosphoSitePlus
T880 Phosphorylation PhosphoSitePlus
T891 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
T900 Phosphorylation PhosphoSitePlus
N940 N-Glycosylation GlyGen 23090970, 24190977
Y1027 Phosphorylation PhosphoSitePlus
S1036 Phosphorylation PhosphoSitePlus
T1219 Phosphorylation PhosphoSitePlus
Y1228 Phosphorylation PhosphoSitePlus
K1322 Ubiquitination PhosphoSitePlus
K1386 Ubiquitination PhosphoSitePlus
K1392 Ubiquitination PhosphoSitePlus
Y1397 Phosphorylation PhosphoSitePlus
K1417 Ubiquitination PhosphoSitePlus
Y1422 Phosphorylation PhosphoSitePlus
Y1428 Phosphorylation PhosphoSitePlus
S1431 Phosphorylation PhosphoSitePlus
S1484 Phosphorylation PhosphoSitePlus
T1486 Phosphorylation PhosphoSitePlus
R1492 Methylation PhosphoSitePlus
Y1662 Phosphorylation PhosphoSitePlus
K1685 Ubiquitination PhosphoSitePlus
T1694 Phosphorylation PhosphoSitePlus
S1695 Phosphorylation PhosphoSitePlus
K1706 Ubiquitination PhosphoSitePlus
Y1717 Phosphorylation PhosphoSitePlus
T1720 Phosphorylation PhosphoSitePlus
Y1793 Phosphorylation PhosphoSitePlus
Y1818 Phosphorylation PhosphoSitePlus
K1824 Ubiquitination PhosphoSitePlus
T1826 Phosphorylation PhosphoSitePlus
S1833 Phosphorylation PhosphoSitePlus
T1835 Phosphorylation PhosphoSitePlus
K1851 Ubiquitination PhosphoSitePlus
Y1939 Phosphorylation PhosphoSitePlus
Y1946 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S396 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S383 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S383 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S383 L383 Biomuta [ cosmic, cosmic ]
S396 L396 Biomuta [ cosmic ]
R610 W610 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1725 / peritoneum cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
R610 L610 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R610 Q610 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T803 I803 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
T803 A803 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T891 M891 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
S893 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T900 A900 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S1036 L1036 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1036 P1036 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1219 M1219 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1484 L1484 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R1492 Q1492 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R1492 W1492 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic ]
T1694 M1694 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1824 R1824 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1833 F1833 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1851 Q1851 Biomuta DOID:1612 / breast cancer [ cosmic ]