Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13291 / SLAF1_HUMAN
Protein Name Signaling lymphocytic activation molecule precursor
Gene Name Name: SLAMF1
Synonyms:SLAM;
Organism Homo sapiens (Human)

PRO ID PR:Q13291
DAG View
PRO Name signaling lymphocytic activation molecule (human)
Definition A SLAM family member 1 that is encoded in the genome of human.
Short Label hSLAMF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13291 (SLAMF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C32 Methylation IEDB 31844290
S73 Phosphorylation PhosphoSitePlus
N102 N-Glycosylation GlyGen 24190977
N125 N-Glycosylation GlyGen 24190977
T272 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation P06241 (FYN) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 11806999, 10549287, 11477068, ...11099315, 11313386, 18083107, 9774102, 10607564, 11689425, 11389028, 11823424, 14674764, 12545174, 12225753
Y307 Phosphorylation P06239 (LCK) , P06241 (FYN) IntAct   phospho.ELM   PhosphoSitePlus   UniProt 9774102, 11806999
Y327 Phosphorylation P07948 (LYN) , P06241 (FYN) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 11806999, 11099315, 15315965
Site PTM Type PTM Enzyme Score Source PMID
Y281 Phosphorylation P06241 (FYN) HPRD 11806999
Y307 Phosphorylation P06241 (FYN) HPRD 11806999
Y327 Phosphorylation P06241 (FYN) HPRD 11806999


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S73 N73 Biomuta DOID:4159 / skin cancer [ cosmic ]
T272 A272 Biomuta DOID:3571 / liver cancer [ cosmic ]
T279 K279 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T279 M279 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ]
Y307 C307 Biomuta DOID:2531 / hematologic cancer [ cosmic ]