iPTMnet Report for Q13162 (PRDX4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13162 / PRDX4_HUMAN
Protein Name Peroxiredoxin-4 precursor
Gene Name Name: PRDX4
Organism Homo sapiens (Human)

PRO ID PR:Q13162
DAG View
PRO Name peroxiredoxin-4 (human)
Definition A peroxiredoxin-4 that is encoded in the genome of human.
Short Label hPRDX4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13162 (PRDX4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C51 S-Nitrosylation dbSNO 26338901
S68 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
C148 S-Nitrosylation dbSNO 25040305
R173 Methylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
Y191 Phosphorylation PhosphoSitePlus
K208 Acetylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
R230 Methylation PhosphoSitePlus
C245 S-Nitrosylation dbSNO 26338901
K250 Methylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S224 * Biomuta DOID:1324 / lung cancer [ cosmic ]
R230 C230 Biomuta DOID:363 / uterine cancer [ icgc ]
K265 N265 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]