iPTMnet Report for Q12765 (SCRN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q12765 / SCRN1_HUMAN
Protein Name Secernin-1
Gene Name Name: SCRN1
Synonyms:KIAA0193;
Organism Homo sapiens (Human)

PRO ID PR:Q12765
DAG View
PRO Name secernin-1 (human)
Definition A secernin-1 that is encoded in the genome of human.
Short Label hSCRN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q12765 (SCRN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
K18 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
C290 S-Nitrosylation dbSNO 26338901
T297 Phosphorylation PhosphoSitePlus
K306 Acetylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
C324 Methylation IEDB 31844290
C324 S-Nitrosylation dbSNO 26338901, 22178444
K333 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S241 C241 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K349 E349 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]