iPTMnet Report for Q0ZGT2 (NEXN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q0ZGT2 / NEXN_HUMAN
Protein Name Nexilin
Gene Name Name: NEXN
Organism Homo sapiens (Human)

PRO ID PR:Q0ZGT2
DAG View
PRO Name nexilin (human)
Definition A nexilin that is encoded in the genome of human.
Short Label hNEXN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q0ZGT2 (NEXN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K16 Phosphorylation UniProt 18669648, 17081983
S80 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18318008, 18669648, 24275569, 20068231
S87 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
T156 Phosphorylation phospho.ELM 18669648
T158 Phosphorylation phospho.ELM 18669648
S160 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S162 Phosphorylation PhosphoSitePlus
S168 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T181 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
K203 Acetylation PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S241 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
S243 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S357 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
Y361 Phosphorylation PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
S365 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983
T370 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569, 17924679
K405 Acetylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
K446 Acetylation PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
S564 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S569 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T602 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S80 Phosphorylation HPRD 18212344, 18767875, 20058876, ...19007248, 19651622, 18669648, 20068231
T156 Phosphorylation HPRD 18669648, 20068231
T158 Phosphorylation HPRD 18669648, 20068231
S160 Phosphorylation HPRD 18669648
S168 Phosphorylation HPRD 18669648
S218 Phosphorylation HPRD 20068231
S241 Phosphorylation HPRD 20068231
S243 Phosphorylation HPRD 20068231
T298 Phosphorylation HPRD 20068231
S357 Phosphorylation HPRD 18669648, 20068231
T363 Phosphorylation HPRD 20058876
S365 Phosphorylation HPRD 18767875, 18077418, 19664994, ...19664995, 20068231
T370 Phosphorylation HPRD 18077418, 20068231, 17924679
T602 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S87 F87 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ]
K136 N136 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T156 A156 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S160 L160 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S162 L162 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
S243 Y243 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
S313 N313 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S357 P357 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]