Protein Information

Cytoscape View


UniProt AC / UniProt ID Q09428 / ABCC8_HUMAN
Protein Name ATP-binding cassette sub-family C member 8
Gene Name Name: ABCC8
Synonyms:HRINS,SUR,SUR1;
Organism Homo sapiens (Human)

PRO ID PR:Q09428
DAG View
PRO Name ATP-binding cassette sub-family C member 8 (human)
Definition An ATP-binding cassette sub-family C member 8 that is encoded in the genome of human.
Short Label hABCC8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q09428 (ABCC8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K528 Ubiquitination PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
Y798 Phosphorylation PhosphoSitePlus
K889 Ubiquitination PhosphoSitePlus
K903 Ubiquitination PhosphoSitePlus
T949 Phosphorylation PhosphoSitePlus
S1072 Phosphorylation IEDB 35494241
S1324 Phosphorylation PhosphoSitePlus
Y1353 Phosphorylation PhosphoSitePlus
S1355 Phosphorylation PhosphoSitePlus
S1356 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S1072 I1072 Biomuta DOID:2021 / placenta cancer [ cosmic ]
S1324 R1324 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1356 F1356 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1356 C1356 Biomuta [ cosmic ]