iPTMnet Report for Q08AM6 (VAC14)
Protein Information
UniProt AC / UniProt ID | Q08AM6 / VAC14_HUMAN |
Protein Name | Protein VAC14 homolog |
Gene Name | Name: VAC14 Synonyms:TAX1BP2,TRX; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q08AM6 |
PRO Name | protein VAC14 homolog (human) |
Definition | A protein VAC14 that is encoded in the genome of human. |
Short Label | hVAC14 |
Category | organism-gene |
Q08AM6 (VAC14) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
T11 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
K35 | Ubiquitination | score1 | PhosphoSitePlus | |||
S68 | Phosphorylation | score1 | IEDB | 35494241 | ||
K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
K151 | Ubiquitination | score1 | PhosphoSitePlus | |||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y185 | Phosphorylation | score1 | PhosphoSitePlus | |||
S186 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y190 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y296 | Phosphorylation | score1 | PhosphoSitePlus | |||
K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
T499 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
T508 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S509 | Phosphorylation | score1 | PhosphoSitePlus | |||
S517 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S519 | Phosphorylation | score1 | PhosphoSitePlus | |||
T520 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y646 | Phosphorylation | score1 | PhosphoSitePlus | |||
K740 | Ubiquitination | score1 | PhosphoSitePlus | |||
S743 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y748 | Phosphorylation | score1 | PhosphoSitePlus | |||
K757 | Ubiquitination | score1 | PhosphoSitePlus | |||
S770 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T11 | Phosphorylation | score0 | HPRD | 18691976 | ||
Y296 | Phosphorylation | score0 | HPRD | 18452278 | ||
T499 | Phosphorylation | score0 | HPRD | 18691976 | ||
T508 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 20068231 | ||
S509 | Phosphorylation | score0 | HPRD | 20068231 | ||
S517 | Phosphorylation | score0 | HPRD | 18691976, 18669648 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K21 | N21 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K35 | N35 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
S517 | Y517 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T520 | I520 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |