iPTMnet Report for Q08945 (SSRP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08945 / SSRP1_HUMAN
Protein Name FACT complex subunit SSRP1
Gene Name Name: SSRP1
Synonyms:FACT80;
Organism Homo sapiens (Human)

PRO ID PR:Q08945
DAG View
PRO Name FACT complex subunit SSRP1 (human)
Definition A FACT complex subunit SSRP1 that is encoded in the genome of human.
Short Label hSSRP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08945 (SSRP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
T4 Phosphorylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
S17 Phosphorylation HPRD   PhosphoSitePlus 20068231
R22 Methylation PhosphoSitePlus
K33 Acetylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K90 Acetylation PhosphoSitePlus
K90 Methylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K100 Acetylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K105 Sumoylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T111 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...35138101, 32522876, 34019948, 32119511, 28510447, 33465208
T111 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
K143 Methylation PhosphoSitePlus
T170 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18077418, 20068231
T209 Phosphorylation PhosphoSitePlus
K228 Acetylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K233 Acetylation PhosphoSitePlus   UniProt 19608861
K233 Ubiquitination PhosphoSitePlus
S258 Phosphorylation HPRD   PhosphoSitePlus 20068230
Y270 Phosphorylation HPRD   PhosphoSitePlus 20068231
S278 Phosphorylation HPRD   PhosphoSitePlus 20068231
K304 Ubiquitination PhosphoSitePlus
S307 Phosphorylation HPRD   PhosphoSitePlus 20068231
S309 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y311 Phosphorylation HPRD   PhosphoSitePlus 15592455
S315 Phosphorylation PhosphoSitePlus
K319 Acetylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
K364 Acetylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
R381 Methylation PhosphoSitePlus
R408 Methylation PhosphoSitePlus
K413 Acetylation PhosphoSitePlus   UniProt 19608861
K413 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
S437 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 17081983, ...18452278
Y438 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983
Y441 Phosphorylation HPRD   PhosphoSitePlus 19651622, 19664995, 18452278
S444 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 21406692, ...23186163, 17081983, 20230923, 19664994, 18220336, 15302935, 19007248, 18452278, 19651622, 18669648, 19690332, 24275569, 18707149, 20166139, 18318008, 19415658, 20068231
Y452 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983, 20068231
S471 Phosphorylation PhosphoSitePlus   UniProt 24275569
S510 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15659405
K542 Acetylation PhosphoSitePlus
K548 Acetylation PhosphoSitePlus
Y554 Phosphorylation HPRD   phospho.ELM 17081983
S561 Phosphorylation HPRD   phospho.ELM 17081983
K566 Ubiquitination PhosphoSitePlus
S567 Phosphorylation HPRD 20068231
S578 Phosphorylation HPRD   PhosphoSitePlus 20068231
K579 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
K612 Acetylation PhosphoSitePlus
K612 Ubiquitination PhosphoSitePlus
Y614 Phosphorylation PhosphoSitePlus
S621 Phosphorylation HPRD 20068231
K623 Acetylation PhosphoSitePlus
S641 Phosphorylation HPRD   PhosphoSitePlus 20068231
T642 Phosphorylation HPRD 20068231
S644 Phosphorylation HPRD   PhosphoSitePlus 20068231
R645 Methylation PhosphoSitePlus
S647 Phosphorylation HPRD 20068231
S649 Phosphorylation HPRD 20068231
S652 Phosphorylation PhosphoSitePlus
S653 Phosphorylation PhosphoSitePlus
S657 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 21406692, 17287340, 19007248, ...20068231, 15659405
S659 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19007248, ...20068231
K661 Acetylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
S662 Phosphorylation HPRD   PhosphoSitePlus 20068231
S667 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19651622, 18669648, 20068231
S668 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 19651622, ...18669648, 20068231
S671 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18452278, ...19651622, 18669648, 20068231
S672 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 19691289, 18452278, ...19651622, 18669648, 20068231
S673 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18452278, 19651622, ...18669648, 20068231
S678 Phosphorylation PhosphoSitePlus
S688 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15659405
T696 Phosphorylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K15 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S17 F17 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R22 L22 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R22 Q22 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R22 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
K33 E33 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K67 N67 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K90 R90 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K90 T90 Biomuta DOID:1324 / lung cancer [ cosmic ]
K100 N100 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K228 E228 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S307 L307 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S309 F309 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K325 E325 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S349 P349 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R381 C381 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R381 H381 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
K566 N566 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S641 Y641 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S641 T641 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
S649 F649 Biomuta DOID:4159 / skin cancer [ cosmic ]
S653 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S672 F672 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S699 G699 Biomuta DOID:363 / uterine cancer [ icgc ]