Protein Information

Cytoscape View


UniProt AC / UniProt ID Q07075 / AMPE_HUMAN
Protein Name Glutamyl aminopeptidase
Gene Name Name: ENPEP
Organism Homo sapiens (Human)

PRO ID PR:Q07075
DAG View
PRO Name glutamyl aminopeptidase (human)
Definition A glutamyl aminopeptidase that is encoded in the genome of human.
Short Label hENPEP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q07075 (ENPEP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S63 O-Glycosylation GlyGen 30459171
T64 O-Glycosylation GlyGen 30459171
S66 O-Glycosylation GlyGen 30459171
S68 O-Glycosylation GlyGen 30459171
N98 N-Glycosylation GlyGen   UniProt 23888046
N124 N-Glycosylation GlyGen   UniProt 19159218
S151 Phosphorylation PhosphoSitePlus
N197 N-Glycosylation GlyGen   UniProt 23888046
N324 N-Glycosylation GlyGen   UniProt 23090970, 23888046, 19159218, ...29391424, 24190977
N340 N-Glycosylation GlyGen   UniProt 23888046
N554 N-Glycosylation GlyGen   UniProt 23888046
N567 N-Glycosylation GlyGen 29391424
N589 N-Glycosylation GlyGen 29391424
N597 N-Glycosylation GlyGen   UniProt 23888046
N607 N-Glycosylation GlyGen   UniProt 16335952, 29391424, 19159218
N678 N-Glycosylation GlyGen   UniProt 23888046
N763 N-Glycosylation GlyGen   UniProt 19159218, 23888046
N773 N-Glycosylation GlyGen   UniProt 19159218
N793 N-Glycosylation GlyGen 29391424
N801 N-Glycosylation GlyGen   UniProt 23888046
N828 N-Glycosylation GlyGen   UniProt 29391424, 23888046
T830 Phosphorylation PhosphoSitePlus
T945 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T64 M64 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T64 P64 Biomuta DOID:1612 / breast cancer [ cosmic ]
S68 L68 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S68 * Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
N124 K124 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S151 P151 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N340 H340 Biomuta DOID:363 / uterine cancer [ icgc ]
N567 K567 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N567 S567 Biomuta DOID:4159 / skin cancer [ cosmic ]
N793 S793 Biomuta DOID:4159 / skin cancer [ cosmic ]
T945 N945 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]