iPTMnet Report for Q06945 (SOX4)
Protein Information
UniProt AC / UniProt ID | Q06945 / SOX4_HUMAN |
Protein Name | Transcription factor SOX-4 |
Gene Name | Name: SOX4 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q06945 |
PRO Name | transcription factor SOX-4 (human) |
Definition | A transcription factor SOX-4 that is encoded in the genome of human. |
Short Label | hSOX4 |
Category | organism-gene |
Q06945 (SOX4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
T54 | Phosphorylation | score1 | PhosphoSitePlus | |||
R75 | Methylation | score1 | PhosphoSitePlus | |||
S81 | Phosphorylation | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
K95 | Acetylation | score3 | PhosphoSitePlus UniProt | 26291311 | ||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
S143 | Phosphorylation | score1 | PhosphoSitePlus | |||
S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
K154 | Acetylation | score1 | PhosphoSitePlus | |||
S161 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
S175 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
S185 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
K192 | Acetylation | score1 | PhosphoSitePlus | |||
K196 | Acetylation | score1 | PhosphoSitePlus | |||
K197 | Acetylation | score1 | PhosphoSitePlus | |||
K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
K213 | Acetylation | score1 | PhosphoSitePlus | |||
K213 | Ubiquitination | score1 | PhosphoSitePlus | |||
K217 | Acetylation | score1 | PhosphoSitePlus | |||
K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
K261 | Ubiquitination | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score0 | HPRD | 15345747 | ||
S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S354 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T54 | P54 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K91 | E91 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K118 | E118 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
S148 | C148 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S174 | I174 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K192 | E192 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S348 | P348 | Biomuta | DOID:10534 / stomach cancer [ icgc ] |