iPTMnet Report for Q05329 (GAD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q05329 / DCE2_HUMAN
Protein Name Glutamate decarboxylase 2
Gene Name Name: GAD2
Synonyms:GAD65;
Organism Homo sapiens (Human)

PRO ID PR:Q05329
DAG View
PRO Name glutamate decarboxylase 2 (human)
Definition A glutamate decarboxylase 2 that is encoded in the genome of human.
Short Label hGAD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q05329 (GAD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus   UniProt 8999827
S6 Phosphorylation PhosphoSitePlus   UniProt 8999827
S10 Phosphorylation PhosphoSitePlus   UniProt 8999827
S13 Phosphorylation PhosphoSitePlus   UniProt 8999827
T95 Phosphorylation PhosphoSitePlus   RLIMS-P 26780456
Y169 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
T515 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
Y547 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 F3 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S13 L13 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T296 R296 Biomuta DOID:1324 / lung cancer [ cosmic ]
T296 K296 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T515 A515 Biomuta DOID:1319 / brain cancer [ icgc ]
S546 N546 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]