iPTMnet Report for Q05193 (DNM1)
Protein Information
UniProt AC / UniProt ID | Q05193 / DYN1_HUMAN |
Protein Name | Dynamin-1 |
Gene Name | Name: DNM1 Synonyms:DNM; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q05193 |
PRO Name | dynamin-1 (human) |
Definition | A dynamin-1 that is encoded in the genome of human. |
Short Label | hDNM1 |
Category | organism-gene |
Q05193 (DNM1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
T214 | Phosphorylation | score1 | PhosphoSitePlus | |||
R217 | Methylation | score1 | PhosphoSitePlus | |||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y231 | Phosphorylation | P12931 (SRC) | score3 | PhosphoSitePlus Signor | 9880482 | |
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
R271 | Methylation | score1 | PhosphoSitePlus | |||
S302 | Phosphorylation | score1 | PhosphoSitePlus | |||
S306 | Phosphorylation | score1 | PhosphoSitePlus | |||
S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y354 | Phosphorylation | score1 | PhosphoSitePlus | |||
K376 | Ubiquitination | score1 | PhosphoSitePlus | |||
T411 | Phosphorylation | score1 | PhosphoSitePlus | |||
S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
T438 | Phosphorylation | score1 | PhosphoSitePlus | |||
T443 | Phosphorylation | score1 | PhosphoSitePlus | |||
S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
K523 | Ubiquitination | score1 | PhosphoSitePlus | |||
K598 | Acetylation | score1 | PhosphoSitePlus | |||
S668 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y669 | Phosphorylation | score1 | PhosphoSitePlus | |||
T684 | O-Glycosylation | score1 | GlyGen | 30379171, 34725712 | ||
Y732 | Phosphorylation | score1 | PhosphoSitePlus | |||
S774 | Phosphorylation | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P | 18088087, 15302935, 23908769, ... | ||
T776 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935, 18088087 | ||
S777 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus | 17437541, 17081983 | ||
S778 | Phosphorylation | P17252 (PRKCA) | score4 | neXtProt phospho.ELM PhosphoSitePlus | 18088087, 15302935, 12855954, ... | |
T780 | Phosphorylation | Q00535 (CDK5) | score4 | neXtProt phospho.ELM PhosphoSitePlus | 15302935, 17376771 | |
S795 | Phosphorylation | Q13627 (DYRK1A) | score3 | PhosphoSitePlus Signor | 15287745 | |
S822 | Phosphorylation | score1 | PhosphoSitePlus | |||
S851 | Phosphorylation | score1 | PhosphoSitePlus | |||
S857 | Phosphorylation | Q13627 (DYRK1A) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor | 15287745, 22857010 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y231 | Phosphorylation | P12931 (SRC) | score1 | HPRD | 9880482 | |
T411 | Phosphorylation | score0 | HPRD | 18491316 | ||
Y597 | Phosphorylation | P12931 (SRC) | score2 | HPRD | 9880482, 12011079 | |
S774 | Phosphorylation | Q00535 (CDK5) | score2 | HPRD | 19651622, 18088087, 12855954 | |
T776 | Phosphorylation | score0 | HPRD | 19651622, 18088087, 17081983 | ||
S777 | Phosphorylation | score0 | HPRD | 17081983 | ||
S778 | Phosphorylation | Q00535 (CDK5) | score2 | HPRD | 19651622, 18088087, 12855954 | |
T780 | Phosphorylation | score0 | HPRD | 19651622 | ||
S795 | Phosphorylation | P17252 (PRKCA) | score1 | HPRD | 10766777 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y231 | Phosphorylation | P12931 (SRC) | score1 | HPRD | 9880482 | |
T411 | Phosphorylation | score0 | HPRD | 18491316 | ||
Y597 | Phosphorylation | P12931 (SRC) | score2 | HPRD | 9880482, 12011079 | |
S774 | Phosphorylation | Q00535 (CDK5) | score2 | HPRD | 19651622, 18088087, 12855954 | |
T776 | Phosphorylation | score0 | HPRD | 19651622, 18088087, 17081983 | ||
S777 | Phosphorylation | score0 | HPRD | 17081983 | ||
S778 | Phosphorylation | Q00535 (CDK5) | score2 | HPRD | 19651622, 18088087, 12855954 | |
T780 | Phosphorylation | score0 | HPRD | 19651622 | ||
S795 | Phosphorylation | P17252 (PRKCA) | score1 | HPRD | 10766777 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S61 | C61 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
R217 | H217 | Biomuta | DOID:1612 / breast cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] | |
S261 | Y261 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S264 | P264 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ] | |
R271 | C271 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y354 | C354 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y597 | C597 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
K598 | N598 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
Y732 | H732 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S822 | P822 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |