iPTMnet Report for Q03393 (PTS)
Protein Information
| UniProt AC / UniProt ID | Q03393 / PTPS_HUMAN |
| Protein Name | 6-pyruvoyl tetrahydrobiopterin synthase |
| Gene Name | Name: PTS |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q03393 |
| PRO Name | 6-pyruvoyl tetrahydrobiopterin synthase (human) |
| Definition | A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of human. |
| Short Label | hPTS |
| Category | organism-gene |
DAG ViewQ03393 (PTS) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S19 | Phosphorylation | Q13976 (PRKG1) , Q13237 (PRKG2) | score4 | HPRD neXtProt phospho.ELM PhosphoSitePlus Signor UniProt | 23186163, 24275569, 18669648, ... | |
| S21 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S23 | Phosphorylation | score0 | HPRD | 20068231 | ||
| K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T58 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y128 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K143 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K131 | Q131 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
