iPTMnet Report for Q02539 (H1-1)
Protein Information
UniProt AC / UniProt ID | Q02539 / H11_HUMAN |
Protein Name | Histone H1.1 |
Gene Name | Name: H1-1 Synonyms:H1F1,HIST1H1A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q02539 |
PRO Name | histone H1.1 (human) |
Definition | A histone H1.1 that is encoded in the genome of human. |
Short Label | hH1-1 |
Category | organism-gene |
Q02539 (H1-1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus | 7499230, 20068231, 17043054 | ||
T4 | Phosphorylation | P06493 (CDK1) | score4 | HPRD phospho.ELM | 7499230, 17043054 | |
K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
K26 | Acetylation | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
K67 | Sumoylation | score1 | PhosphoSitePlus | |||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
K78 | Acetylation | score1 | PhosphoSitePlus | |||
K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
S81 | Phosphorylation | score1 | PhosphoSitePlus | |||
K88 | Acetylation | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
S89 | Phosphorylation | score1 | PhosphoSitePlus | |||
S92 | Phosphorylation | score1 | PhosphoSitePlus | |||
K93 | Acetylation | score1 | PhosphoSitePlus | |||
K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
T95 | Phosphorylation | score1 | PhosphoSitePlus | |||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
T102 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
K109 | Acetylation | score1 | PhosphoSitePlus | |||
K109 | Methylation | score1 | PhosphoSitePlus | |||
K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
T152 | Phosphorylation | P24941 (CDK2) | score3 | neXtProt PhosphoSitePlus | 20551309 | |
T162 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17287340 | ||
S165 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S166 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S183 | Phosphorylation | Q15369 (ELOC) , P50750 (CDK9) | score3 | neXtProt PhosphoSitePlus Signor | 20551309 | |
T204 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S61 | L61 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T95 | R95 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
T95 | M95 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K100 | R100 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K109 | R109 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K125 | N125 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S165 | F165 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |