iPTMnet Report Q02363 ID2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q02363 / ID2_HUMAN
Protein Name	DNA-binding protein inhibitor ID-2
Gene Name	Name: ID2 Synonyms:BHLHB26;
Organism	Homo sapiens (Human)

PRO ID	PR:Q02363 DAG View
PRO Name	DNA-binding protein inhibitor ID-2 (human)
Definition	A DNA-binding protein inhibitor ID-2 that is encoded in the genome of human.
Short Label	hID2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q02363 (ID2) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S5	Phosphorylation		score4	HPRD IEDB neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor	35440621, 34171305, 33936100, ...32157095, 9372912, 9029153, 32387766, 29493099, 27869121, 26110849
	S5	Phosphorylation	P24941 (CDK2)	score3	HPRD phospho.ELM Signor	9029153
	K12	Ubiquitination		score1	PhosphoSitePlus
	S14	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163, 24275569
	S16	Phosphorylation		score1	PhosphoSitePlus
	T27	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	26735018
	T27	Phosphorylation	Q9Y463 (DYRK1B)	score2	PhosphoSitePlus	26735018
	Y43	Phosphorylation		score1	PhosphoSitePlus
	S44	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S5	Phosphorylation		score2	PRO	9029153

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000036427 (hID2/iso:1/Phos:1)	pS5		PRO	9029153

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S5	C5	Biomuta		DOID:1324 / lung cancer [ cosmic ]
S16	L16	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
T27	A27	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
Y43	D43	Biomuta		DOID:363 / uterine cancer [ icgc ]