iPTMnet Report for Q02153 (GUCY1B1)
Protein Information
UniProt AC / UniProt ID | Q02153 / GCYB1_HUMAN |
Protein Name | Guanylate cyclase soluble subunit beta-1 |
Gene Name | Name: GUCY1B1 Synonyms:GUC1B3,GUCSB3,GUCY1B3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q02153 |
PRO Name | guanylate cyclase soluble subunit beta-1 (human) |
Definition | A guanylate cyclase soluble subunit beta-1 that is encoded in the genome of human. |
Short Label | hGUCY1B1 |
Category | organism-gene |
Q02153 (GUCY1B1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y192 | Phosphorylation | P12931 (SRC) | score2 | PhosphoSitePlus | 16079134 | |
K471 | Ubiquitination | score1 | PhosphoSitePlus | |||
C497 | Methylation | score1 | IEDB | 31844290 | ||
Y540 | Phosphorylation | score1 | PhosphoSitePlus | |||
K561 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y567 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K165 | N165 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y540 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |