Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02153 / GCYB1_HUMAN
Protein Name Guanylate cyclase soluble subunit beta-1
Gene Name Name: GUCY1B1
Synonyms:GUC1B3,GUCSB3,GUCY1B3;
Organism Homo sapiens (Human)

PRO ID PR:Q02153
DAG View
PRO Name guanylate cyclase soluble subunit beta-1 (human)
Definition A guanylate cyclase soluble subunit beta-1 that is encoded in the genome of human.
Short Label hGUCY1B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02153 (GUCY1B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K165 Ubiquitination PhosphoSitePlus
Y192 Phosphorylation P12931 (SRC) PhosphoSitePlus 16079134
K471 Ubiquitination PhosphoSitePlus
C497 Methylation IEDB 31844290
Y540 Phosphorylation PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
Y567 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K165 N165 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y540 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]