iPTMnet Report for Q02086 (SP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02086 / SP2_HUMAN
Protein Name Transcription factor Sp2
Gene Name Name: SP2
Synonyms:KIAA0048;
Organism Homo sapiens (Human)

PRO ID PR:Q02086
DAG View
PRO Name transcription factor Sp2 (human)
Definition A transcription factor Sp2 that is encoded in the genome of human.
Short Label hSP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02086 (SP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T55 Phosphorylation PhosphoSitePlus
T63 Phosphorylation PhosphoSitePlus
S78 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S83 Phosphorylation PhosphoSitePlus
S187 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...32938750, 30059200, 35254053, 35132862, 21606357, 31492838, 30620550
S188 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...30059200, 30620550, 35132862, 31492838, 35254053
T192 Phosphorylation PhosphoSitePlus
S196 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...30059200, 30620550, 35132862, 31492838, 35254053
S235 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
S371 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...30059200, 30620550, 35132862, 31492838, 35254053
S371 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
T383 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus
T550 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S569 Phosphorylation PhosphoSitePlus
K605 Ubiquitination PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S78 Phosphorylation HPRD 18669648, 20068231
T192 Phosphorylation HPRD 19413330
T550 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S187 L187 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T192 P192 Biomuta DOID:1612 / breast cancer [ cosmic ]
S380 P380 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
T535 M535 Biomuta DOID:9256 / colorectal cancer [ cosmic ]