iPTMnet Report for Q01546 (KRT76)
Protein Information
UniProt AC / UniProt ID | Q01546 / K22O_HUMAN |
Protein Name | Keratin, type II cytoskeletal 2 oral |
Gene Name | Name: KRT76 Synonyms:KRT2B,KRT2P; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q01546 |
PRO Name | keratin, type II cytoskeletal 2 oral (human) |
Definition | A keratin, type II cytoskeletal 2 oral that is encoded in the genome of human. |
Short Label | hKRT76 |
Category | organism-gene |
Q01546 (KRT76) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y59 | Phosphorylation | score1 | PhosphoSitePlus | |||
S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
R85 | Methylation | score1 | PhosphoSitePlus | |||
R110 | Methylation | score1 | PhosphoSitePlus | |||
K188 | Ubiquitination | score1 | PhosphoSitePlus | |||
T189 | Phosphorylation | score1 | PhosphoSitePlus | |||
K193 | Acetylation | score1 | PhosphoSitePlus | |||
K193 | Methylation | score1 | PhosphoSitePlus | |||
K193 | Sumoylation | score1 | PhosphoSitePlus | |||
K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
K200 | Acetylation | score1 | PhosphoSitePlus | |||
K200 | Ubiquitination | score1 | PhosphoSitePlus | |||
K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y361 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y376 | Phosphorylation | score1 | PhosphoSitePlus | |||
T385 | Phosphorylation | score1 | PhosphoSitePlus | |||
T427 | Phosphorylation | score1 | PhosphoSitePlus | |||
K487 | Acetylation | score1 | PhosphoSitePlus | |||
R495 | Methylation | score1 | PhosphoSitePlus | |||
S541 | Phosphorylation | score1 | PhosphoSitePlus | |||
S542 | Phosphorylation | score1 | PhosphoSitePlus | |||
S544 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y549 | Phosphorylation | score1 | PhosphoSitePlus | |||
S620 | Phosphorylation | score0 | HPRD | 20068231 | ||
S626 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S18 | F18 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S21 | F21 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
Y59 | * | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
R110 | K110 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
R110 | S110 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K188 | N188 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
S196 | F196 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S541 | G541 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
S626 | A626 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S626 | F626 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |