iPTMnet Report for Q01105 (SET)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01105 / SET_HUMAN
Protein Name Protein SET
Gene Name Name: SET
Organism Homo sapiens (Human)

PRO ID PR:Q01105
DAG View
PRO Name protein SET (human)
Definition A protein SET that is encoded in the genome of human.
Short Label hSET
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01105 (SET) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18669648, 24275569, ...20068231, 17924679
P11 Acetylation UniProt 19608861
K15 Phosphorylation UniProt 21406692, 20068231
P24 Phosphorylation UniProt 21406692, 20068231
S28 Phosphorylation PhosphoSitePlus   UniProt 23186163
K39 Acetylation PhosphoSitePlus
R57 Methylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus   UniProt 23186163
K68 Sumoylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K72 Acetylation PhosphoSitePlus
K83 Acetylation PhosphoSitePlus
K83 Methylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K90 Acetylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
Y119 Phosphorylation PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Methylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
Y140 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
K150 Acetylation PhosphoSitePlus   UniProt 19608861
K150 Ubiquitination PhosphoSitePlus
K154 Acetylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
K167 Acetylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K172 Acetylation PhosphoSitePlus   UniProt 19608861
K172 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
T186 O-Glycosylation GlyGen 30379171, 34019948, 28510447, ...35138101, 33465208
K189 Ubiquitination PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K7 Acetylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
S9 Phosphorylation P67870 (CSNK2B) , P19784 (CSNK2A2) , P68400 (CSNK2A1) , P48736 (PIK3CG) HPRD   PhosphoSitePlus   Signor 21419339, 8131851, 17245428, ...23374587
K11 Acetylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
S15 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983, 20068231, ...20230923
T23 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 17287340, 17081983, ...20068231
S24 Phosphorylation HPRD   PhosphoSitePlus 8131851, 18452278, 19651622, ...18669648, 20068231
K26 Ubiquitination PhosphoSitePlus
S50 Phosphorylation HPRD 19651622, 19664994, 20068231, ...18452278
K70 Acetylation PhosphoSitePlus
S93 Phosphorylation P48736 (PIK3CG) PhosphoSitePlus 21419339
K119 Ubiquitination PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
S148 Phosphorylation HPRD 19651622, 20068231
S171 Phosphorylation Q9BZL6 (PRKD2) neXtProt   PhosphoSitePlus 23251465
S178 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 L2 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
P11 L11 Biomuta DOID:1324 / lung cancer [ cosmic ]
S24 P24 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K90 N90 Biomuta DOID:4362 / cervical cancer [ icgc ]
S171 I171 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S178 N178 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T186 M186 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S191 N191 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]