iPTMnet Report for Q00169 (PITPNA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q00169 / PIPNA_HUMAN
Protein Name Phosphatidylinositol transfer protein alpha isoform
Gene Name Name: PITPNA
Synonyms:PITPN;
Organism Homo sapiens (Human)

PRO ID PR:Q00169
DAG View
PRO Name phosphatidylinositol transfer protein alpha isoform (human)
Definition A phosphatidylinositol transfer protein alpha isoform that is encoded in the genome of human.
Short Label hPITPNA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q00169 (PITPNA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Sumoylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
Y57 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
T58 Phosphorylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
Y93 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
Y140 Phosphorylation PhosphoSitePlus
R146 Methylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
S165 Phosphorylation phospho.ELM   PhosphoSitePlus 15322105
K178 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K215 Acetylation PhosphoSitePlus   UniProt 19608861
K215 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K60 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y93 F93 Biomuta DOID:4159 / skin cancer [ cosmic ]
K110 E110 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R146 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
R146 Q146 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S165 F165 Biomuta DOID:363 / uterine cancer [ icgc ]