Protein Information

Cytoscape View


UniProt AC / UniProt ID P98194 / AT2C1_HUMAN
Protein Name Calcium-transporting ATPase type 2C member 1
Gene Name Name: ATP2C1
Synonyms:KIAA1347,PMR1L;ORFNames:HUSSY-28;
Organism Homo sapiens (Human)

PRO ID PR:P98194
DAG View
PRO Name calcium-transporting ATPase type 2C member 1 (human)
Definition A calcium-transporting ATPase type 2C member 1 that is encoded in the genome of human.
Short Label hATP2C1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P98194 (ATP2C1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Acetylation IEDB 34357683
K8 Ubiquitination PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
C195 Methylation IEDB 31844290
K229 Ubiquitination PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
Y452 Phosphorylation PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K514 Ubiquitination PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
T557 Phosphorylation PhosphoSitePlus
T558 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
K589 Ubiquitination PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
T804 Phosphorylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
S826 Phosphorylation PhosphoSitePlus
K831 Ubiquitination PhosphoSitePlus
K897 Acetylation PhosphoSitePlus
K907 Ubiquitination PhosphoSitePlus
S913 Phosphorylation PhosphoSitePlus
S914 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Site PTM Type PTM Enzyme Score Source PMID
T420 Phosphorylation HPRD 20068231
S911 Phosphorylation HPRD 20068231
S914 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T420 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T420 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S70 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T420 Phosphorylation HPRD 20068231
S911 Phosphorylation HPRD 20068231
S914 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K514 Q514 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S519 L519 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T558 P558 Biomuta DOID:363 / uterine cancer [ icgc ]
T558 A558 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K589 N589 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S637 L637 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K831 T831 Biomuta DOID:263 / kidney cancer [ cosmic ]
S911 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S911 L911 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
S913 L913 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ]