Protein Information

Cytoscape View


UniProt AC / UniProt ID P86790 / CCZ1B_HUMAN
Protein Name Vacuolar fusion protein CCZ1 homolog B
Gene Name Name: CCZ1B
Synonyms:C7orf28B;
Organism Homo sapiens (Human)

PRO ID PR:P86790
DAG View
PRO Name vacuolar fusion protein CCZ1 homolog B (human)
Definition A vacuolar fusion protein CCZ1 homolog B that is encoded in the genome of human.
Short Label hCCZ1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P86790 (CCZ1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895
S10 Phosphorylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus   UniProt 23186163
K82 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
C141 Methylation IEDB 31844290
K162 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
S266 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...18220336
K295 Ubiquitination PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
S370 Phosphorylation HPRD 20068231
K372 Ubiquitination PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
Y437 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K55 Q55 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K55 N55 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S76 N76 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K88 T88 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K162 N162 Biomuta DOID:363 / uterine cancer [ icgc ]
K246 T246 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K246 E246 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]