iPTMnet Report for P83916 (CBX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P83916 / CBX1_HUMAN
Protein Name Chromobox protein homolog 1
Gene Name Name: CBX1
Synonyms:CBX;
Organism Homo sapiens (Human)

PRO ID PR:P83916
DAG View
PRO Name chromobox protein homolog 1 (human)
Definition A chromobox protein homolog 1 that is encoded in the genome of human.
Short Label hCBX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P83916 (CBX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Acetylation PhosphoSitePlus
K9 Methylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
Y21 Phosphorylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K33 Acetylation PhosphoSitePlus
K35 Acetylation PhosphoSitePlus
K35 Methylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K41 Acetylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
T51 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   RLIMS-P   Signor 18438399, 19657222
S70 Phosphorylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
T73 Phosphorylation PhosphoSitePlus
T77 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
K84 Acetylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
S89 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 19651622, ...24275569, 20166139, 20068231
S91 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 20068231
S98 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
R111 Methylation PhosphoSitePlus
R115 Methylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K139 Acetylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
C156 S-Nitrosylation dbSNO 24105792
S162 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
S175 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
K180 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R111 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R115 Q115 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
R115 L115 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R115 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S175 * Biomuta DOID:1612 / breast cancer [ cosmic ]
K180 N180 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]