iPTMnet Report for P80370 (DLK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P80370 / DLK1_HUMAN
Protein Name Protein delta homolog 1 precursor
Gene Name Name: DLK1
Synonyms:DLK;
Organism Homo sapiens (Human)

PRO ID PR:P80370
DAG View
PRO Name protein delta homolog 1 (human)
Definition A protein delta homolog 1 that is encoded in the genome of human.
Short Label hDLK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P80370 (DLK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S94 O-Glycosylation GlyGen   UniProt 7925474
N100 N-Glycosylation GlyGen   UniProt 7925474
T143 O-Glycosylation GlyGen   UniProt 7925474
S163 O-Glycosylation GlyGen   UniProt 7925474
N165 N-Glycosylation GlyGen   UniProt 7925474
N172 N-Glycosylation GlyGen   UniProt 7925474
S214 O-Glycosylation GlyGen   UniProt 7925474
T222 O-Glycosylation GlyGen   UniProt 7925474
S251 O-Glycosylation GlyGen   UniProt 7925474
S251 Phosphorylation IEDB 35494241
T256 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 30459171, 22171320
S260 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 7925474
T269 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
Y353 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N100 K100 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S163 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S251 I251 Biomuta DOID:363 / uterine cancer [ icgc ]
S260 N260 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S355 N355 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]