Protein Information

Cytoscape View


UniProt AC / UniProt ID P78423 / X3CL1_HUMAN
Protein Name Fractalkine precursor
Gene Name Name: CX3CL1
Synonyms:FKN;ORFNames:A-152E5.2;
Organism Homo sapiens (Human)

PRO ID PR:P78423
DAG View
PRO Name fractalkine (human)
Definition A fractalkine that is encoded in the genome of human.
Short Label hCX3CL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78423 (CX3CL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N33 N-Glycosylation GlyGen 29741879
T97 Phosphorylation PhosphoSitePlus
T153 O-Glycosylation GlyGen 30459171
T183 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 30237853, 22171320
S199 O-Glycosylation GlyGen 30459171
S208 O-Glycosylation GlyGen 30459171
S225 Phosphorylation PhosphoSitePlus
S253 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 30459171, 19838169, ...22171320
T272 O-Glycosylation GlyGen 30459171
T318 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T329 O-Glycosylation GlyGen   UniProt 30459171, 19838169, 22171320
T338 O-Glycosylation GlyGen 22171320
S391 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T183 M183 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T272 M272 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S391 L391 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]