iPTMnet Report for P78413 (IRX4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78413 / IRX4_HUMAN
Protein Name Iroquois-class homeodomain protein IRX-4
Gene Name Name: IRX4
Synonyms:IRXA3;
Organism Homo sapiens (Human)

PRO ID PR:P78413
DAG View
PRO Name iroquois-class homeodomain protein IRX-4 (human)
Definition An iroquois-class homeodomain protein IRX-4 that is encoded in the genome of human.
Short Label hIRX4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78413 (IRX4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T153 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S153 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K240 E240 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S258 T258 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S430 F430 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S473 L473 Biomuta DOID:10534 / stomach cancer [ cosmic ]