iPTMnet Report for P78395 (PRAME)
Protein Information
UniProt AC / UniProt ID | P78395 / PRAME_HUMAN |
Protein Name | Melanoma antigen preferentially expressed in tumors |
Gene Name | Name: PRAME Synonyms:MAPE; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P78395 |
PRO Name | melanoma antigen preferentially expressed in tumors (human) |
Definition | A melanoma antigen preferentially expressed in tumors that is encoded in the genome of human. |
Short Label | hPRAME |
Category | organism-gene |
P78395 (PRAME) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S16 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
K158 | Acetylation | score1 | PhosphoSitePlus | |||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
K184 | Acetylation | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
K251 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K224 | N224 | Biomuta | [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |