iPTMnet Report for P78368 (CSNK1G2)
Protein Information
| UniProt AC / UniProt ID | P78368 / KC1G2_HUMAN |
| Protein Name | Casein kinase I isoform gamma-2 |
| Gene Name | Name: CSNK1G2 Synonyms:CK1G2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P78368 |
| PRO Name | casein kinase I isoform gamma-2 (human) |
| Definition | A casein kinase I isoform gamma-2 that is encoded in the genome of human. |
| Short Label | hCSNK1G2 |
| Category | organism-gene |
DAG ViewP78368 (CSNK1G2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| R25 | Methylation | score1 | PhosphoSitePlus | |||
| S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S32 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S33 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K51 | Acetylation | score1 | PhosphoSitePlus | |||
| K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y67 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C133 | Methylation | score1 | IEDB | 31844290 | ||
| T136 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T151 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| T158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y195 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T259 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K266 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T336 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S366 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976 | ||
| T367 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976 | ||
| T377 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K404 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S410 | Phosphorylation | score1 | PhosphoSitePlus |
P78368 (CSNK1G2) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| P84022 (SMAD3) | S418 | score3 | neXtProt Signor | 18794808 | |
| Q14457 (BECN1) | T406 | score2 | PhosphoSitePlus | 26008601 | |
| Q14457 (BECN1) | S409 | score2 | PhosphoSitePlus | 26008601 | |
| Q9Y5P4 (CERT1) | S132 | score3 | PhosphoSitePlus Signor | 19005213 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R25 | W25 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
| Y71 | H71 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| Y93 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| K167 | N167 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y195 | D195 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T259 | M259 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K266 | R266 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K266 | Q266 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S410 | * | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S410 | L410 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ] |
 |