iPTMnet Report for P78364 (PHC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78364 / PHC1_HUMAN
Protein Name Polyhomeotic-like protein 1
Gene Name Name: PHC1
Synonyms:EDR1,PH1;
Organism Homo sapiens (Human)

PRO ID PR:P78364
DAG View
PRO Name polyhomeotic-like protein 1 (human)
Definition A polyhomeotic-like protein 1 that is encoded in the genome of human.
Short Label hPHC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78364 (PHC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y32 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
T309 Phosphorylation PhosphoSitePlus
T320 O-Glycosylation GlyGen 33214551, 35138101, 34019948, ...29351928, 35132862, 31492838, 35289036, 35254053, 28657654
T322 O-Glycosylation GlyGen 33214551, 35138101, 34019948, ...29351928, 35132862, 31492838, 35289036, 35254053, 28657654
S324 O-Glycosylation GlyGen 33214551, 35138101, 29351928, ...35132862, 30620550, 34019948, 31492838, 35289036, 35254053, 28657654
S324 Phosphorylation PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
T554 O-Glycosylation GlyGen 33214551, 35138101, 34019948, ...29351928, 35132862, 31492838, 35289036, 35254053, 28657654
S555 O-Glycosylation GlyGen 33214551, 35138101, 29351928, ...35132862, 30620550, 34019948, 31492838, 35289036, 35254053, 28657654
S645 Phosphorylation PhosphoSitePlus   UniProt 21406692
S653 Phosphorylation HPRD   PhosphoSitePlus 18491316
S657 Phosphorylation HPRD   PhosphoSitePlus 18491316
S664 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18491316
S669 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18491316
K763 Ubiquitination PhosphoSitePlus
S786 Phosphorylation HPRD   PhosphoSitePlus 19413330
K793 Acetylation PhosphoSitePlus
K794 Acetylation PhosphoSitePlus
S815 Phosphorylation PhosphoSitePlus
Y850 Phosphorylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
S862 Phosphorylation PhosphoSitePlus
S888 Phosphorylation PhosphoSitePlus
S889 Phosphorylation PhosphoSitePlus
Y890 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus
S898 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19664995, 19690332
T918 Phosphorylation PhosphoSitePlus
T922 Phosphorylation PhosphoSitePlus   UniProt 19690332
K997 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T309 I309 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T320 I320 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S555 P555 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S653 C653 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S786 I786 Biomuta DOID:3571 / liver cancer [ cosmic ]
S815 Y815 Biomuta DOID:363 / uterine cancer [ icgc ]
S889 I889 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T918 I918 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]